Comprehensive & Implant Dentistry in Durham, NC
Durham Dentists in North Carolina
If you’re looking for top-rated dentists in Durham, NC, O2 Dental Group is here for you. We provide a full range of services, including cleanings, fillings, cosmetic dentistry, and more. Contact us today to learn how we can help with your smile.
Your Go-To Dental Clinic in Durham, NC

Finding an affordable dentist in Durham, NC, shouldn’t be a challenge. At O2 Dental Group, we make quality dental care comfortable and accessible for every patient. If you’re new in town or just searching for a better dental experience, our team is here to give you and your family a reason to smile.
We’re proud to be known as one of the best dentists in Durham — trusted by families, professionals, and students alike for modern, full-service care under one roof.
A Dental Experience Built Around You
At O2 Dental Group in Durham, we believe in better care through better communication. We don’t rush patients in and out. Instead, our Durham, NC, dentists take time to understand your goals, explain your treatment clearly, and make sure you feel confident every step of the way.
You’ll be treated with care, respect, and genuine compassion, whether you’re here for a routine cleaning or a dental emergency. That’s what makes us the best dentist in Durham for families and individuals alike.

What Patients Say About Their Experience with Our Durham Dentists
Patients often tell us they’ve finally found the best dentist in Durham, NC, where care feels personal and the results speak for themselves. From check-in to aftercare, our team makes every visit comfortable and stress-free. That’s why so many locals recommend our Durham dental clinic.


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Convenient, affordable dentists near you.
Complete Dental Care in Durham, NC
At our Durham dental clinic, we offer comprehensive care for every member of your family, right here under one roof. Our experienced team of dentists in Durham, NC, provides a full range of services designed to keep your smile healthy and pain-free.
Meet Your Dental Team in Durham, NC
At our Durham dental clinic, you’ll find a dedicated team of skilled professionals who care about more than just teeth; we care about people. As trusted Durham dentists, we take the time to build lasting relationships with every patient, so you always feel confident in your care and proud of your smile.
Dr. Vanessa Cross
Hello! I’m Dr. Cross, and I’m excited to be joining the O2 family! I was raised in Florida but came to NC in 2010 and decided to make it my permanent home. I graduated from UNC Chapel Hill with a major in Afro-American Studies and a double minor in African Studies and History. I took some time off between undergrad and dental school and worked as a bartender at Sup Dogs on Franklin Street! During this time, I also completed post-bacc studies at UNC Greensboro and worked as an oral surgical assistant before applying to dental school. I attended dental school at UNC Chapel Hill and have been fortunate enough to provide service and care to those in need. When I’m not working, you can find me traveling or spending time with family, friends, and my spoiled fur baby named Lilly. I enjoy hanging around downtown Durham and am a frequent visitor at DPAC and Durham Bull Games. I look forward to working with you all towards better oral health!

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Best Dentist in Durham, NC, and its Surrounding Communities
Discovering a confident, healthy smile starts with choosing the right dentist in Durham, NC—and at O2 Dental Group, we make that decision easy. If you’re a local resident or just passing through, our warm, welcoming Durham dental clinic offers modern care for patients of all ages.
Located just off Durham-Chapel Hill Blvd at 3219 Watkins Rd #103, our office is easy to find and even easier to feel at home in. Just minutes from Chapel Hill and The Streets at Southpoint, our dental clinic in Durham, NC, blends the latest dental technology with a personalized, compassionate approach.
If you’ve been searching for the best dentist in Durham, look no further. We’re proud to care for patients from across the region, including nearby neighborhoods like Chapel Hill, Hope Valley, and Old West Durham.
New patients are always welcome, and we’re committed to creating a calm, pressure-free environment that makes every visit as stress-free as possible. It’s no wonder so many families return year after year for quality care delivered with kindness.
And to better serve our diverse community, our team includes both English- and Spanish-speaking staff—¡se habla español!
Why Choose O2 Dental Group in Durham?
When you’re searching for a dentist in Durham, NC, you’ll find plenty of options, but not all Durham dentists offer the convenience, comfort, and advanced care that O2 Dental Group provides. Here’s what sets us apart:
Modern, Welcoming Environment
Our office is designed with your comfort in mind—clean, calming, and equipped with modern amenities. We also have a bilingual team fluent in English and Spanish to make sure you feel understood and at ease during every visit
Complete Dental Care in One Place
We provide a full range of services for patients of all ages, whether it’s a routine cleaning, dental implants, or pediatric dentistry. You won’t need to travel between multiple offices—our Durham dental clinic has everything under one roof.
Affordable Payment Options
Everyone deserves a healthy smile. That’s why we offer flexible financing, accept most major insurance plans, and provide access to our O2 Advantage Plan, making us a top choice for anyone looking for an affordable dentist in Durham, NC.
Advanced Dental Technology
Experience the latest in digital dentistry, including 3D imaging, same-day crowns, and digital dentures. Our investment in modern tools means more efficient appointments and better long-term results.
Focused on Your Comfort
We’re committed to making your visit stress-free with thoughtful touches like scented towels, noise-canceling headphones, and a welcoming atmosphere. Our goal is to redefine what it means to visit the best dentist in Durham, NC.
Same-Day & Emergency Appointments
Unexpected dental issues? Our extended hours and same-day emergency care make it easy to get help when you need it most, without the long wait
Visit O2 Dental
Group, Your Trusted Durham Dentist
Choosing the right dental provider matters, and at O2 Dental Group, we’re proud to be the Durham dentist families turn to for high-quality, reliable care. With a full range of services, modern technology, and a compassionate team, we make it easier to stay on top of your oral health.
If you’re searching for a dentist in Durham, NC, O2 Dental Group is here to welcome you. See why so many consider us the best dentist Durham has to offer.

FAQs About Dentists in Durham, NC
How much should a dentist cost?
The cost depends on the treatment, but most dentists in Durham, NC, offer pricing transparency. Preventive services like cleanings and exams are typically budget-friendly, especially at an affordable dentist in Durham, NC, such as the O2 Dental Group!
What services do dentists in Durham typically offer?
Most Durham dentists provide preventive, restorative, cosmetic, and emergency dental services. At O2 Dental Group, our Durham dental clinic offers everything from cleanings and fillings to same-day crowns, implants, and pediatric care — all under one roof.
Are there affordable dentists in Durham, NC?
Yes! If you’re searching for an affordable dentist in Durham, NC, O2 Dental Group offers flexible payment options, accepts most major insurance plans, and even has a membership plan (the O2 Advantage Plan) to help keep care budget-friendly.
Does it matter what dentist you go to?
Absolutely. The quality of your care, comfort, and long-term oral health depends on your provider. Not all Durham dentists offer the same experience, so choosing a trusted dentist in Durham with a focus on patient satisfaction is important.
What is the difference between a DDS and a DMD dentist?
There is no difference in care—both are fully qualified dental degrees. The distinction is simply based on where the dentist graduated. Many dentists in Durham hold either title, but what matters more is their training, technology, and patient experience.
What should I do if I need a dentist near me in Durham, NC, for an emergency?
If you need urgent care, our dentist in Durham, NC, offers same-day emergency appointments. We understand that dental issues don’t always happen during business hours, which is why we have extended availability at our Durham dental clinic.
How often should I see a dentist in Durham?
It’s recommended to see a Durham dentist every six months for cleanings and exams. Regular visits help prevent more serious issues and keep your smile healthy long-term.
What is a bridge for teeth?
A dental bridge is a fixed prosthetic that replaces missing teeth using surrounding teeth for support. It’s a common restorative solution offered by many dentists in Durham, NC, including our team at O2 Dental Group.
Where can I find a dentist near me in Durham, NC, that offers everything in one place?
O2 Dental Group is your one-stop Durham dental clinic, with preventive, restorative, pediatric, and emergency care all under one roof — a convenient option when you’re searching for a dentist in Durham, NC.
DENTISTRY IN DURHAM, NC
Schedule Today!
We look forward to meeting you. Call (919) 646-3849 or request an appointment online to set up your first visit. We’ll be in touch soon.
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8:00am – 2:00pm (every other Friday)
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